J. Vormann and T. Goedecke
نویسنده
چکیده
The regulation of the pH value inside and outside of the cells is an essential precondition for the functional ability of the enzyme-controlled metabolic processes of our body. The ratio of acids to bases is not only important for a healthy metabolism, it also determines the structure and function of proteins, permeability of cell membranes, distribution of electrolytes, and functioning of connective tissue. On the basis of the present state of scientific knowledge, longterm disturbances of the natural acid-base balance are receiving increasing attention as a risk factor for the pathogenesis of chronic diseases like, for example, osteoporosis particularly since in the past, the pH regulation was medically taken for granted and the required buffering capacity of the organism was considered as almost inexhaustible. Nowadays, latent acidosis resulting from a gradual reduction of the buffer reserves, mainly due to nutritional influences, is increasingly becoming the focus of scientific studies.
منابع مشابه
Acid-Base Homeostasis: Latent Acidosis as a Cause of Chronic Diseases
In the healthy human being, the blood has a pH value of 7.4. Even slight deviations from this value may lead to s e v e re disturbances in metabolism which may even be life-threatening. It is for this reason that the body`s extensive buffer systems ensure that the blood pH is maintained between the very narrow limits of 7.37 and 7.43. These buffer systems bind and neutralize the additional prot...
متن کاملAcid-Base Homeostasis: Latent Acidosis as a Cause of Chronic Diseases Latest findings on the beneficial disease-modifying aspects of an adequate dietary base supply
In the healthy human being, the blood has a pH value of 7.4. Even slight deviations from this value may lead to severe disturbances in metabolism which may even be life-threatening. It is for this reason that the body`s extensive buffer systems ensure that the blood pH is maintained between the very narrow limits of 7.37 and 7.43. These buffer systems bind and neutralize the additional protons ...
متن کاملMg Deprivation Elicits Rapid Ca Uptake and Activates Ca /Calcineurin Signaling in Saccharomyces cerevisiae
متن کامل
Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain.
The cause of low back pain is heterogeneous, it has been hypothesised that a latent chronic acidosis might contribute to these symptoms. It was tested whether a supplementation with alkaline minerals would influence symptoms in patients with low back pain symptoms. In an open prospective study 82 patients with chronic low back pain received daily 30 g of a lactose based alkaline multimineral su...
متن کاملRelative Mal’tsev Categories
We define relative regular Mal’tsev categories and give an overview of conditions which are equivalent to the relative Mal’tsev axiom. These include conditions on relations as well as conditions on simplicial objects. We also give various examples and counterexamples.
متن کامل